Head of the Department of Therapeutic mRNA Technology (f/m/d)
Date: 28 Oct 2026
Location: Würzburg
Company: Helmholtz-Zentrum für Infektionsforschung GmbH

Job announcement no. 799
The Helmholtz Institute for RNA-based Infection Research (HIRI) is seeking, to start as soon as possible, a
Head of the Department of Therapeutic mRNA Technology (f/m/d)
The Helmholtz Institute for RNA-based Infection Research (HIRI) is the first institution of its kind worldwide to combine ribonucleic acid (RNA) research with infection biology. Based on novel findings from our strong basic research program, our long-term goal is to develop innovative therapeutic approaches to better diagnose and treat human infections. HIRI is a joint venture of the Helmholtz Center for Infection Research (HZI) in Braunschweig and the University of Würzburg (JMU) and is located on the Würzburg Medical Campus.
Further information at www.helmholtz-hiri.de.
Responsibilities:
- Establishment of an independent research program combined with the leadership and strategic development of an internationally visible department at the interface of RNA biochemistry, RNA technologies and RNA medicine
- Development, operation and deployment of a GLP platform for mRNA/LNP production, quality control, high-throughput screening and preclinical studies
- Development and optimization of programmable mRNA constructs for vaccines and therapeutics
- Establishment of collaborations between HIRI/HZI and JMU, the German Center for Infection Research (DZIF), the Helmholtz Association, as well as with clinical, biotechnology and pharmaceutical partners
- Supporting early-career researchers, team development, securing external funding, teaching, and academic self-administration
Requirements:
- A university degree in chemistry, biochemistry, biology, molecular biology, biophysics, pharmacy, medicine or a comparable discipline, as well as an outstanding PhD
- An internationally recognized and independent research profile in RNA research, with particular expertise in at least one of the following areas: RNA biochemistry, RNA biophysics, RNA technologies, RNA medicine or RNA-based infectious disease research
- Proven expertise in the development and optimization of mRNA platforms and RNA-based drug technologies
- Several years of experience in leading RNA research and RNA design programs in academic and biopharmaceutical settings
- Experience with high-throughput screening, automated workflows, or quantitative and computational modeling
- Experience in preclinical translation and with collaborations in the biotechnology sector, the pharmaceutical industry, or clinical research
- Extensive experience in leading research groups, industry staff, research institutes, or core facilities, with a focus on gender and diversity
- Experience in supervising PhD students and postdoctoral researchers, and supporting early-career researchers
- A research profile of internationally recognized standing and a strong publication record as per career stage
- Comprehensive understanding of laboratory techniques and workflows in molecular biology
- International network, strong collaborative skills, excellent spoken and written English skills; knowledge of German or the willingness to learn German
- A result-oriented and responsible working style with a high degree of initiative
- A ‘can-do’ attitude and the ability to develop creative solutions
- A commitment to equality and diversity
We offer you:
- Support with a subsequent application for a professorship (W3) at the Faculty of Medicine, University of Würzburg
- A prominent leadership position at an internationally recognized research institute
- Establishment and management of an independent department and its research program
- Attractive personnel and financial resources
- State-of-the-art infrastructure for RNA research, microbiology and molecular biology in a new institute building
- Close collaboration with the HZI, HIRI and JMU, as well as with national and international partners
- Flexible working hours, part-time models, and the opportunity to work from home
- A corporate culture of appreciation and promotion of equal opportunities
- Extensive professional development and advanced training opportunities
- A family office to support family and career; childcare offers
- Additional public service benefits
- Possibility of an employer subsidy for the job ticket
People with severe disabilities and equivalent professional qualifications who are suitable for the position are given preference. In order to protect your rights, we ask you to provide us with a clearly recognizable reference to the existence of a degree of severe disability in your cover letter or resume.
The position is held at the Helmholtz Centre for Infection Research GmbH (HZI) in Braunschweig. The place of employment is Würzburg. In collaboration with the University of Würzburg (JMU), we are aiming to initiate a subsequent appointment procedure for a W3 professorship in the near future.
The HZI is actively committed to equality, diversity and integration. For this reason, the HZI pursues the goal of professional equality between women and men and expressly welcomes applications from qualified women. The position is suitable for part-time work.
For further information please contact Professor Jörg Vogel, phone +49 931 31 82575, email: joerg.vogel@uni-wuerzburg.de. https://www.helmholtz-hiri.de/en/research/organisation/people/person/joerg-vogel/
Please apply via our career portal.
Please include a cover letter, resume, an overview of how you intend to implement DEI (Diversity, Equity and Inclusion) in your future laboratory (maximum half a page), a two-page project description, references, certificates and a list of your publications. Please refrain from sending a photo.
We look forward to receiving your application!
